AG473

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

AG473 是人 A431 细胞中 EGFR 的抑制剂。在大肠杆菌中表达脑膜炎奈瑟氏球菌的 Ag473 脂蛋白、创伤弧菌的鞭毛蛋白 FlaB 和结核分枝杆菌 (mHsp70) 的热休克蛋白 70，作为单一蛋白和与感染性法氏囊 VP2 蛋白的融合蛋白疾病病毒（IBDV）。

AG473 is an inhibitor of EGFR in human A431 cells.Expressed the Ag473 lipoprotein from Neisseria meningitides, flagellin FlaB from Vibrio vulnificus and heat shock protein 70 from Mycobacterium tuberculosis (mHsp70) in Escherichia coli as single proteins and fusion proteins with VP2 protein of infectious bursal disease virus (IBDV).?Both cellular and humoral adjuvanticities of the three TLR ligands were compared by immunization of mice in two different ways.?Among the three co-administered TLR ligands, recombinant Ag473 lipoprotein exhibited the highest cellular and humoral adjuvanticities, including promotion of IL-4, IL-12, IFN-γ and IBDV VP2-specific antibody production.?Among the three genetically fused TLR ligands, fusion with Ag473 D1 domain exhibited the highest cellular and humoral adjuvanticities.

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Angiogenesis

FGFR

FGFR

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133550-22-8

265.26

C16H11NO3?

>98% (HPLC)

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OC1=C(O)C=C(\\C=C(/C#N)C(=O)C2=CC=CC=C2)C=C1

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(-20℃)

With Ice Pack

≥ 2 years