
AC1-IN-1
CAS No. 2762422-55-7
AC1-IN-1 ( —— )
产品货号. M28481 CAS No. 2762422-55-7
AC1-IN-1 是 1 型腺苷酸环化酶的选择性抑制剂 (AC1, IC50 = 0.54 μM)。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥2811 | 有现货 |
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10MG | ¥4496 | 有现货 |
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25MG | ¥7266 | 有现货 |
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50MG | ¥9963 | 有现货 |
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100MG | ¥13365 | 有现货 |
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500MG | ¥26649 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称AC1-IN-1
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述AC1-IN-1 是 1 型腺苷酸环化酶的选择性抑制剂 (AC1, IC50 = 0.54 μM)。
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产品描述AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 μM).(In Vitro):In HEK293 cells, AC1-IN-1 (30 μM, 1 hours) shows nontoxic to this human cell line.(In Vivo):AC1-IN-1 (5.6 mg/kg; i.v.) displays modest, yet statistically significant, antiallodynic effects at 1 h post-treatment compared to the 0 min time point.
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体外实验AC1-IN-1 (compound 38; HEK293 cells; 30 μM, 1 hours) shows nontoxic to this human cell line.Cell Cytotoxicity Assay Cell Line:HEK293 cells Concentration:30 μM Incubation Time:1 hours Result:Showed nontoxic to HEK293 cells.
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体内实验AC1-IN-1 (5.6 mg/kg; i.v.) displays modest, yet statistically significant, antiallodynic effects at 1 h post-treatment compared to the 0 min (allodynic) time point. Animal Model:Male and female C57BL/6N mice (complete Freund’s adjuvant inflammatory pain model)Dosage:5.6 mg/kg (dissolved in 10% DMSO/10% Cremaphor/80% saline)Administration:Intravenous injection; 2 hours Result:Displayed modest, yet statistically significant, antiallodynic effects.
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同义词——
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通路Others
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靶点Other Targets
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受体Apoptosis inhibitor
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研究领域——
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适应症——
化学信息
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CAS Number2762422-55-7
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分子量355.37
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分子式C18H18FN5O2
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 25 mg/mL (70.35 mM)
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SMILESCCC1=CC(=O)N=C(N2N=C(C)C=C2NC(=O)C2=C(F)C=CC(C)=C2)N1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
产品手册




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