AB-680 ( —— )

产品货号. M23955 CAS No. 2105904-82-1

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

AB-680
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

AB-680 is a highly potent, reversible, and selective inhibitor of CD73 (an ectonucleotidase, Ki: 4.9 pM for hCD73) with anti-tumor activity.
产品描述

AB-680 is a highly potent, reversible, and selective inhibitor of CD73 (an ectonucleotidase, Ki: 4.9 pM for hCD73) with anti-tumor activity, displays >10,000-fold selectivity over related ectonucleotidases CD39.
同义词

——
通路

Others
靶点

Other Targets
受体

CD73
研究领域

——
适应症

——

CAS Number

2105904-82-1
分子量

580.8
分子式

C20H24ClFN4O9P2
纯度

>98% (HPLC)
溶解度

DMSO:180 mg/mL (309.91 mM; Need ultrasonic)
SMILES

C[C@@H](c(cccc1)c1F)Nc1cc(Cl)nc2c1cnn2[C@@H]([C@@H]1O)O[C@H](COP(CP(O)(O)=O)(O)=O)[C@H]1O
化学全称

——

1.Lawson KV, et al. Discovery and Characterization of AB680, a Potent and Selective Small-Molecule CD73 Inhibitor for Cancer Immunotherapy.

计算器

产品手册

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