AA147 ( ATF6-activator-147 )

产品货号. M22642 CAS No. 393121-74-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

AA147
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

AA147 is a small molecule endoplasmic reticulum (ER) proteostasis regulator.?The selectively activates ATF6 arm of the unfolded protein response (UPR) .
产品描述

AA147 is a small molecule endoplasmic reticulum (ER) proteostasis regulator.?The selectively activates ATF6 arm of the unfolded protein response (UPR) .It acts as a prodrug that preferentially triggers ATF6 signaling through a mechanism involving localized metabolic activation and selective covalent modification of ER resident proteins that regulate ATF6 activity.
同义词

ATF6-activator-147
通路

Others
靶点

Other Targets
受体

ATF6
研究领域

——
适应症

——

1. Christina COOLEY, et al. Regulators of the endoplasmic reticulum proteostasis network. WO2017117430A1.

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