A-381393
CAS No. 726174-00-1
A-381393 ( —— )
产品货号. M20141 CAS No. 726174-00-1
A-381393 是一种选择性脑渗透性多巴胺 D4 受体拮抗剂(Kis:对于人多巴胺 D4.2/D4.4/D4.7 受体为 1.9/1.5/1.6 nM)。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ¥640 | 有现货 |
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| 5MG | ¥988 | 有现货 |
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| 10MG | ¥1604 | 有现货 |
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| 25MG | ¥2989 | 有现货 |
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| 50MG | ¥4301 | 有现货 |
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| 100MG | ¥6221 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
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生物学信息
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产品名称A-381393
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述A-381393 是一种选择性脑渗透性多巴胺 D4 受体拮抗剂(Kis:对于人多巴胺 D4.2/D4.4/D4.7 受体为 1.9/1.5/1.6 nM)。
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产品描述A-381393 is a selective and brain penetrate dopamine D4 receptor antagonist (Kis: 1.9/1.5/1.6 nM for human dopamine D4.2/D4.4/D4.7 receptor).
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体外实验A-381393 exhibits weak affinity at 5-HT1A, Sigma 2, Adenoceptor α1A, Adenoceptor α2C, Histamine H1, with Kis of 1365, 8600, 2044, 1912 and 2962 nM, respectively.
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体内实验——
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同义词——
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通路GPCR/G Protein
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靶点Dopamine Receptor
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受体D4
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研究领域——
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适应症——
化学信息
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CAS Number726174-00-1
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分子量320.43
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分子式C20H24N4
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纯度>98% (HPLC)
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溶解度DMSO: 50 mg/mL (156.04 mM)
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SMILESCc1ccc(cc1C)N1CCN(Cc2nc3ccccc3[nH]2)CC1
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化学全称2-[[4-(34-dimethylphenyl)piperazin-1-yl]methyl]-1H-benzimidazole
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Nakane M et al. 2-[4-(34-Dimethylphenyl)piperazin-1-ylmethyl]-1H benzoimidazole (A-381393) a selective dopamine D4 receptor antagonist. Neuropharmacology. 2005 Jul;49(1):112-21.
产品手册
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