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A-196(b)

CAS No. 1982372-88-2

A-196(b) ( SGC A-196; SGC A 196; SGC A196 )

产品货号. M17412 CAS No. 1982372-88-2

A-196 is a potent and selective inhibitor of SUV420 h1 and SUV420 h2 with IC50 values of 0.025 and 0.144 μM, respectively.

纯度: 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥356 有现货
5MG ¥583 有现货
10MG ¥786 有现货
25MG ¥1588 有现货
50MG ¥2957 有现货
100MG ¥4479 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    A-196(b)
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    A-196 is a potent and selective inhibitor of SUV420 h1 and SUV420 h2 with IC50 values of 0.025 and 0.144 μM, respectively.
  • 产品描述
    SGC A-196 is a potent inhibitor of SUV420H1 (IC50 = 25 nM) and SUV420H2 (IC50 = 144 nM), a closely related pair of proteins which catalyze the di- and tri-methylation of H4K20.
  • 同义词
    SGC A-196; SGC A 196; SGC A196
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    SUV420H1;SUV420H2
  • 研究领域
    Cancer
  • 适应症
    ——

化学信息

  • CAS Number
    1982372-88-2
  • 分子量
    359.25
  • 分子式
    C18H16Cl2N4
  • 纯度
    98%
  • 溶解度
    DMSO : ≥ 31 mg/mL; 86.29 mM
  • SMILES
    Clc1cc3c(cc1Cl)c(nnc3NC2CCCC2)c4ccncc4
  • 化学全称
    Cyclopentyl-(6,7-dichloro-4-pyridin-4-yl-phthalazin-1-yl)-amine

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Bromberg KD,etal.The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity.Nat Chem Biol. 2017 Mar;13(3):317-324.
产品手册
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