8-Hydroxyguanosine
CAS No. 3868-31-3
8-Hydroxyguanosine ( —— )
产品货号. M22909 CAS No. 3868-31-3
8-羟基鸟苷 (8-OHG) 是测量核酸和脂质氧化损伤率的标志物。帕金森病 (PD) 患者脑脊液中 8-OHG 的浓度约为对照组的三倍。脑脊液中8-OHG的浓度随着病程的延长而显着下降。然而,与对照组相比,PD患者血清中8-OHG的浓度没有显着改变。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ¥300 | 有现货 |
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| 5MG | ¥494 | 有现货 |
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| 10MG | ¥786 | 有现货 |
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| 25MG | ¥1571 | 有现货 |
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| 50MG | ¥2519 | 有现货 |
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| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
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生物学信息
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产品名称8-Hydroxyguanosine
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述8-羟基鸟苷 (8-OHG) 是测量核酸和脂质氧化损伤率的标志物。帕金森病 (PD) 患者脑脊液中 8-OHG 的浓度约为对照组的三倍。脑脊液中8-OHG的浓度随着病程的延长而显着下降。然而,与对照组相比,PD患者血清中8-OHG的浓度没有显着改变。
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产品描述8-hydroxyguanosine (8-OHG) is a marker for measuring the rate of oxidative damage to nucleic acids and lipids.The concentration of 8-OHG in CSF in Parkinson's disease (PD) patients is approximately three-fold that in controls. The concentration of 8-OHG in CSF decreased significantly with the duration of disease. However, the concentration of 8-OHG in serum was not significantly altered in PD patients compared to that in controls.
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体外实验——
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number3868-31-3
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分子量299.24
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分子式C10H13N5O6
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纯度>98% (HPLC)
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溶解度DMSO:240 mg/mL (802.03 mM)
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SMILESOC[C@@H]1[C@H]([C@H]([C@H](N2C(NC3=C2N=C(N)NC3=O)=O)O1)O)O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Harman SM, et al. Urinary excretion of three nucleic acid oxidation adducts and isoprostane F(2)alpha measured by liquid chromatography-mass spectrometry in smokers, ex-smokers, and nonsmokers. Free Radic Biol Med. 2003 Nov 15;35(10):1301-9.
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