6RK73 ( —— )

产品货号. M26038 CAS No. 1895050-66-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

拼团产品询价大包装询价加入购物车

产品名称

6RK73
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

6RK73 is a covalent irreversible and specific UCHL1 inhibitor (IC50: 0.23 μM).
产品描述

6RK73 is a covalent irreversible and specific UCHL1 inhibitor (IC50: 0.23 μM). 6RK73 shows almost no inhibition of UCHL3 (IC50: 236 μM).(In Vitro):6RK73 (5 μM; 1-3 hours) treatment displays strong inhibition of the TGFβ-induced pSMAD2 and pSMAD3, and a decrease of TβRI and total SMAD protein levels in MDA-MB-436 cells. 6RK73 (5 μM; 24-48 hours) results in migration significantly slower than the DMSO control group in MDA-MB-436 cells.(In Vivo):6RK73 displays a potent inhibition of breast cancer extravasation in zebrafish.
同义词

——
通路

Others
靶点

Other Targets
受体

Antioxidant
研究领域

——
适应症

——

1.Safranal Attenuates Excitotoxin-Induced Oxidative OLN-93 Cells Injury

计算器

产品手册

关联产品

Gap19 TFA (1507930-5...

Gap19 TFA is a peptide derived from nine amino acids of Cx43 cytoplasmic ring (CL), an effective, selective connexin 43 (Cx43) half-channel blocker.
N-(2-{bis[2-(2,2-dic...

N-(2-{bis[2-(2,2-dichloroacetamido)ethyl]amino}ethyl)-2,2-dichloroacetamide hydrochloride is a chemical compound.
Cajanin

Cajanin has potential hypolipidemic effects,possibly via up-regulating the ABCA1 protein expression,subsequently resulting in increased macrophage cholesterol efflux and RCT, it can significantly improve basal glucose uptake in HepG2 cells, its improving effect is concentration dependent, it exhibits effects stronger than that of rosiglitazone, which has been used as an antidiabetic drug.