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6RK73

CAS No. 1895050-66-4

6RK73 ( —— )

产品货号. M26038 CAS No. 1895050-66-4

6RK73 is a covalent irreversible and specific UCHL1 inhibitor (IC50: 0.23 μM).

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥2535 有现货
10MG ¥4350 有现货
25MG ¥7039 有现货
50MG ¥9639 有现货
100MG ¥12879 有现货
500MG ¥26082 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    6RK73
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    6RK73 is a covalent irreversible and specific UCHL1 inhibitor (IC50: 0.23 μM).
  • 产品描述
    6RK73 is a covalent irreversible and specific UCHL1 inhibitor (IC50: 0.23 μM). 6RK73 shows almost no inhibition of UCHL3 (IC50: 236 μM).(In Vitro):6RK73 (5 μM; 1-3 hours) treatment displays strong inhibition of the TGFβ-induced pSMAD2 and pSMAD3, and a decrease of TβRI and total SMAD protein levels in MDA-MB-436 cells. 6RK73 (5 μM; 24-48 hours) results in migration significantly slower than the DMSO control group in MDA-MB-436 cells.(In Vivo):6RK73 displays a potent inhibition of breast cancer extravasation in zebrafish.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Antioxidant
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1895050-66-4
  • 分子量
    307.4
  • 分子式
    C13H17N5O2S
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    O=C(Nc1ncc(s1)N1CCOCC1)[C@H]1CCN(C1)C#N
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Safranal Attenuates Excitotoxin-Induced Oxidative OLN-93 Cells Injury
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