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6-Methylflavone
CAS No. 29976-75-8
6-Methylflavone ( —— )
产品货号. M21420 CAS No. 29976-75-8
6-Mmethylflavone 是 α1β2γ2L 和 α1β2 GABAA 受体的激活剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | ￥332 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称6-Methylflavone
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述6-Mmethylflavone 是 α1β2γ2L 和 α1β2 GABAA 受体的激活剂。
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产品描述6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors.
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体外实验6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors. 6-Methylflavone enhances the normal response to GABA at recombinant α1β2γ2L and α1β2 GABAA receptors (P<0.0001) at concentrations from 1 to 100 μM. 6-Methylflavone (60 μM) shifts the GABA dose-response curve to the left (n=4, F=16.38, P=0.0004), decreasing the mean EC50 at α1β2γ2L GABAA receptors by 33±5.4%.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体α1β2γ2L GABAA receptor|α1β2 GABAA receptor
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研究领域——
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适应症——
化学信息
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CAS Number29976-75-8
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分子量236.27
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分子式C16H12O2
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纯度>98% (HPLC)
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溶解度DMSO:5 mg/mL (211.62 mM)
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SMILESCC1=CC2=C(C=C1)OC(=CC2=O)C3=CC=CC=C3
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Hall BJ et al. Flumazenil-independent positive modulation of gamma-aminobutyric acid action by 6-methylflavone at human recombinant alpha1beta2gamma2L and alpha1beta2 GABAA receptors. Eur J Pharmacol. 2004 Apr 26;491(1):1-8.
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