4u8C

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

4μ8C 是一种有效的选择性 IRE1 Rnase 抑制剂，IC50 为 76 nM。

4μ8C is a potent and selective IRE1 Rnase inhibitor with IC50 of 76 nM.

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Animal Model:ApoE-/- mice Dosage:10 mg/kg Administration:I.p. injection; daily; for 4 more weeks Result:Led to a significant reduction (45.2%) in atherosclerotic lesion area in en face aorta preparations.

IRE1 Inhibitor III

Others

Other Targets

IRE1 RN/Ase

Other Indications

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14003-96-4

204.18

C11H8O4

>98% (HPLC)

DMSO:19 mg/mL (93.05 mM); Ethanol:<1 mg/mL (<1 mM); Water:<1 mg/mL (<1 mM)

O=CC1=C(O2)C(C(C)=CC2=O)=CC=C1O

7-hydroxy-4-methyl-2-oxo-2H-1-benzopyran-8-carboxaldehyde

(-20℃)

With Ice Pack

≥ 2 years