4-CPPC ( —— )

产品货号. M28169 CAS No. 29553-70-6

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

4-CPPC
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50= 27 μM).
产品描述

4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50= 27 μM).1It is selective for MIF-2 over MIF-1 (IC50= 450 μM). It inhibits MIF-2, but not MIF-1, binding to CD74in vitrowhen used at a concentration of 10 μM. 4-CPPC (5, 10, and 25 μM) inhibits MIF-2-induced ERK1/2 phosphorylation in primary human skin fibroblasts.
同义词

——
通路

Others
靶点

Other Targets
受体

PXR
研究领域

——
适应症

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1.Lin W, et, al. SPA70 is a potent antagonist of human pregnane X receptor. Nat Commun. 2017 Sep 29;8(1):741.

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