23-Butanedione ( Biacetyl | Diacetyl )

产品货号. M19605 CAS No. 431-03-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

23-Butanedione
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

2,3-丁二酮（二乙酰）是一种与爆米花肺疾病有关的分子，目前已被证实与阿尔茨海默病相关的淀粉样β肽毒性有关。二乙酰会加速淀粉样蛋白-β 的聚集，这是阿尔茨海默病的一个标志。
产品描述

23-Butanedione (Diacetyl) the molecule implicated in the disease known as popcorn lung has now been implicated in amyloid-β peptide toxicity associated with Alzheimer’s disease. Diacetyl accelerates amyloid-β aggregation-a hallmark of Alzheimer’s disease. These preliminary findings raise the possibility of long-term neurological toxicity mediated by DA.
体外实验

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体内实验

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同义词

Biacetyl | Diacetyl
通路

Others
靶点

Other Targets
受体

Others
研究领域

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适应症

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1.Heinitz K et al. Toxicity mediated by soluble oligomers of beta-amyloid(1-42) on cholinergic SN56.B5.G4 cells. J Neurochem. 2006 Sep;98(6):1930-45.

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