1,5-Isoquinolinediol
CAS No. 5154-02-9
1,5-Isoquinolinediol ( —— )
产品货号. M17727 CAS No. 5154-02-9
1, 5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50: 0.39 μM).
纯度: 98%
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥470 | 有现货 |
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10MG | ¥705 | 有现货 |
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50MG | ¥1547 | 有现货 |
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100MG | 获取报价 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称1,5-Isoquinolinediol
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述1, 5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50: 0.39 μM).
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产品描述1, 5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50: 0.39 μM). The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis. 1, 5-Isoquinolinediol has been used to study the role of PARP1 in both DNA repair and oxidant stress-induced cell death. This compound can be used with cells in culture and in animals.
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同义词——
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通路Others
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靶点Other Targets
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受体PARP1
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研究领域——
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适应症——
化学信息
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CAS Number5154-02-9
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分子量161.16
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分子式C9H7NO2
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纯度98%
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溶解度——
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SMILESOc1cccc2c1cc[nH]c2=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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3-Hydroxybakuchiol
3-Hydroxybakuchiol exerts cytotoxic and anti-proliferative effects on the TA3/Ha mouse mammary adenocarcinoma cell line and induces a decrease in the mitochondrial transmembrane potential, the activation of caspase-3, the opening of the mitochondrial permeability transport pore (MPTP) and nuclear DNA fragmentation.3-Hydroxybakuchiol has antitumor activity resulting from interactions with the ETC, a system that is already deficient in cancer cells.
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Methyl nomilinate
Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.
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Methyl nomilinate
Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.