1,5-Isoquinolinediol ( —— )

产品货号. M17727 CAS No. 5154-02-9

COA

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HNMR

HPLC

MSDS

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产品名称

1,5-Isoquinolinediol
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

1, 5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50: 0.39 μM).
产品描述

1, 5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50: 0.39 μM). The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis. 1, 5-Isoquinolinediol has been used to study the role of PARP1 in both DNA repair and oxidant stress-induced cell death. This compound can be used with cells in culture and in animals.
同义词

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通路

Others
靶点

Other Targets
受体

PARP1
研究领域

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适应症

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1. Davar D, et al. Role of PARP inhibitors in cancer biology and therapy.[J]. Current Medicinal Chemistry, 2012, 19(23).

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