1,2,3,6-Tetragalloylglucose

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

1,2,3,6-Tetragalloyglucose 具有抗氧化活性，还显示出最有效的抗补体活性 (IC50 = 34 microM)。 1,2,3,6-Tetragalloylglucose 也是 UDP 葡萄糖醛酸基转移酶 1 A1 (UGT1A1, Ki = 1.68 μM) 的有效抑制剂。

1,2,3,6-Tetragalloylglucose has antioxidative activity, it also shows the most potent anticomplement activity (IC50 = 34 microM). 1,2,3,6-Tetragalloylglucose is also a potent inhibitor of UDP glucuronosyltransferase 1 A1 (UGT1A1, Ki = 1.68 μM).(In Vitro):The phenolic 1,2,3,6-Tetragalloylglucose (2), isolated from the stem-bark of Juglans mandshurica was evaluated for its antioxidative activity. The results showed that 1,2,3,6-Tetragalloylglucose exhibited strong scavenging activities against 1,1'-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-azino-bis-(3-ethylbenzenthiazoline-6-sulphonic) acid (ABTS(*+)), and superoxide radicals (O(2)(*-)), and also had a significant inhibitory effect on lipid peroxidation and low-density lipoprotein (LDL) oxidation.

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TeGG | 1,2,3,6-Tetra-O-galloyl-β-D-glucose

Metabolic Enzyme/Protease

LDL

LDL

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79886-50-3

788.576

C34H28O22

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (126.81 mM)

O[C@@H]1[C@@H](COC(=O)c2cc(O)c(O)c(O)c2)O[C@@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@H]1OC(=O)c1cc(O)c(O)c(O)c1

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(-20℃)

With Ice Pack

≥ 2 years