(S,R,S)-AHPC-PEG4-N3 ( VH032-PEG4-N3; VHL Ligand-Linker Conjugates 5; E3 ligase Ligand-Linker Conjugates 4 )

产品货号. M26950 CAS No. 1797406-81-5

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

(S,R,S)-AHPC-PEG4-N3
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

(S,R,S)-AHPC-PEG4-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology.
产品描述

(S,R,S)-AHPC-PEG4-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology.(In Vitro):E3?ligase Ligand-Linker Conjugates 4 together with JQ1 triggers the intracellular destruction of BET proteins.
同义词

VH032-PEG4-N3; VHL Ligand-Linker Conjugates 5; E3 ligase Ligand-Linker Conjugates 4
通路

Others
靶点

Other Targets
受体

ATP-sensitive potassium (KATP) channels
研究领域

——
适应症

——

CAS Number

1797406-81-5
分子量

689.8
分子式

C32H47N7O8S
纯度

>98% (HPLC)
溶解度

——
SMILES

O=C(N[C@@H](C(C)(C)C)C(N(C[C@H](O)C1)[C@@H]1C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)=O)COCCOCCOCCOCCN=[N+]=[N-]
化学全称

——

1.L?ffler C, et al. Pharmacological characterization of the sulphonylurea receptor in rat isolated aorta. Br J Pharmacol. 1997 Feb;120(3):476-80.

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