(E)-SI-2 ( —— )

产品货号. M28929 CAS No. 380537-35-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

(E)-SI-2
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

(E)-SI-2 是一种有效的类固醇受体辅激活因子 3 (SRC-3 或 AIB1) 小分子抑制剂，可以选择性抑制 SRC-3 的内在转录活性，也抑制 SRC-1 和 SRC-2。
产品描述

(E)-SI-2 is a potent small-molecule inhibitor of steroid receptor coactivator-3 (SRC-3 or AIB1) that can selectively inhibit the intrinsic transcriptional activities of SRC-3, also inhibits SRC-1 and SRC-2. It selectively reduces cellular protein levels of SRC-3, but not that of CARM-1, blocks MDA-MB-468 cell growth with an IC50 value of 3.4 nM, but spares normal cells.
体外实验

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体内实验

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同义词

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通路

Others
靶点

Other Targets
受体

Antibacterial
研究领域

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适应症

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1.By Wright, George E.; Xu, Wei-Chu From U.S. (2014), US 8796292 B2 20140805.

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