Nolatrexed Dihydrochloride is the dihydrochloride salt of nolatrexed, a water-soluble lipophilic quinazoline folate analog with antineoplastic activity.

Pyrimidines are heterocyclic six-membered nitrogen-containing carbon ring structures with uracil cytosine and thymine being the basal structures of ribose-containing nucleosides (uridine cytidine and thymidine respectively) or deoxyribose-containing deoxynucleosides and their corresponding ribonucleotides or deoxyribonucleotides.

Glycyrin, one of the main PPAR-gamma ligands of licorice, can significantly decrease the blood glucose levels of genetically diabetic KK-A(y) mice.