TD-165
CAS No. 2305936-56-3
TD-165 ( —— )
产品货号. M27017 CAS No. 2305936-56-3
TD-165 is a PROTAC-based cereblon (CRBN) degrader comprising a?CRBN?ligand binding group, a linker and a?VHL binding group.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥2341 | 有现货 |
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10MG | ¥3872 | 有现货 |
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25MG | ¥6391 | 有现货 |
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50MG | ¥8748 | 有现货 |
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100MG | ¥11988 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称TD-165
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述TD-165 is a PROTAC-based cereblon (CRBN) degrader comprising a?CRBN?ligand binding group, a linker and a?VHL binding group.
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产品描述TD-165 is a PROTAC-based cereblon (CRBN) degrader comprising a?CRBN?ligand binding group, a linker and a?VHL binding group.(In Vitro):Administration of 0.1-10?μM TD-165 for 24 hours resulted in a concentration-dependent decrease in CRBN protein levels in HEK293T cells. Administration of 0-100 nM TD-165 for 24 hours showed a 50% degradation concentration (DC50) of 20.4?nM and a maximum degradation (Dmax) value of 99.6%.
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同义词——
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通路Others
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靶点Other Targets
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受体Bacterial
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研究领域——
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适应症——
化学信息
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CAS Number2305936-56-3
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分子量870.1
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分子式C46H59N7O8S
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纯度>98% (HPLC)
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溶解度——
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SMILESCc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCCCCCNc2cccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c23)C(C)(C)C)cc1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.XiaoyeGeng, et al. Design and fabrication of reversible thermochromic microencapsulated phase change materials for thermal energy storage and its antibacterial activity. Energy. Volume 159, 15 September 2018, Pages 857-869.
产品手册
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