• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

Glycerophosphocholine

CAS No. 28319-77-9

Glycerophosphocholine ( Choline Alfoscerate; Alpha GPC; Choline glycerophosphate )

产品货号. M18359 CAS No. 28319-77-9

Glycerylphosphorylcholine is a natural choline compound found in the brain and in milk. It is also a parasympathomimetic acetylcholine precursor which may have a potential for the treatment of Alzheimer's disease and dementia.

纯度: 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
1G ¥405 有现货

生物学信息

  • 产品名称
    Glycerophosphocholine
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Glycerylphosphorylcholine is a natural choline compound found in the brain and in milk. It is also a parasympathomimetic acetylcholine precursor which may have a potential for the treatment of Alzheimer's disease and dementia.
  • 产品描述
    Choline Alfoscerate, also known as Alpha GPC and L-Alpha glycerylphosphorylcholine, is a component of PHOSPHATIDYLCHOLINES or LECITHINS, in which the two hydroxy groups of GLYCEROL are esterified with fatty acids. Choline Alfoscerate is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. Choline Alfoscerate is used in the treatment of Alzheimer's Disease and other dementias.
  • 同义词
    Choline Alfoscerate; Alpha GPC; Choline glycerophosphate
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    AChE
  • 研究领域
    Neurological Disease
  • 适应症
    ——

化学信息

  • CAS Number
    28319-77-9
  • 分子量
    257.22
  • 分子式
    C8H20NO6P
  • 纯度
    98%
  • 溶解度
    H2O : 500 mg/mL 1943.86 mM; DMSO : ≥ 125 mg/mL 485.97 mM
  • SMILES
    C[N+](C)(C)CCOP(=O)([O-])OC[C@@H](CO)O
  • 化学全称
    (R)-2,3-dihydroxypropyl (2-(trimethylammonio)ethyl) phosphate

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Parnetti L, et al. Cholinergic precursors in the treatment of cognitive impairment of vascular origin: ineffective approaches or need for re-evaluation J Neurol Sci. 2007 Jun 15;257(1-2):264-9.
产品手册
关联产品
  • BRD7389

    BRD7389 is an inhibitor of RSK family kinase with IC50s of 1.5 μM, 2.4 μM, and 1.2 μM for RSK1, RSK2, and RSK3, respectively.

  • Boc-NH-PEG8-CH2CH2CO...

    Boc-NH-PEG8-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

  • Methyl nomilinate

    Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.