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Daminozide
CAS No. 1596-84-5
Daminozide ( Alar | Aminozide | B 995 | DIMG | DMASA | Kylar | SADH | Succinic Acid )
产品货号. M12281 CAS No. 1596-84-5
Daminozide(DMASA; DIMG; B 995) 是一种植物生长调节剂，选择性抑制 KDM2/7 JmjC 亚家族。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 500MG | ￥340 | 有现货 |
|
| 1G | ￥405 | 有现货 |
|
生物学信息
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产品名称Daminozide
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Daminozide(DMASA; DIMG; B 995) 是一种植物生长调节剂，选择性抑制 KDM2/7 JmjC 亚家族。
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产品描述Daminozide(DMASA; DIMG; B 995), a plant growth regulator, selectively inhibits the KDM2/7 JmjC subfamily.(In Vitro):Daminozide has >100-fold selectivity for KDM2/7 subfamily versus other demethylase subfamily members tested (IC50=127 μM for KDM3A, or greater against other demethylases).(In Vivo):Daminozide (200-20000 ppm) has teratogenic and genotoxic effects on model organism Drosophila melanogaster.
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体外实验Daminozide has >100-fold selectivity for KDM2/7 subfamily versus other demethylase subfamily members tested (IC50=127 μM for KDM3A, or greater against other demethylases).
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体内实验Daminozide (200-20000 ppm) has teratogenic and genotoxic effects on model organism Drosophila melanogaster.
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同义词Alar | Aminozide | B 995 | DIMG | DMASA | Kylar | SADH | Succinic Acid
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通路Chromatin/Epigenetic
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靶点Histone Demethylase
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受体KDM2/7 JmjC
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研究领域Cancer
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适应症——
化学信息
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CAS Number1596-84-5
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分子量160.17
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分子式C6H12N2O3
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纯度>98% (HPLC)
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溶解度Soluble in DMSO
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SMILESOC(CCC(NN(C)C)=O)=O
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化学全称4-(2,2-dimethylhydrazinyl)-4-oxobutanoic acid
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Reed DJ, Moore TC, Anderson JD. Science. 1965 Jun 11;148(3676):1469-71.
