Kinesin is eukaryotic-conserved motor proteins that move along MTs with ATP hydrolysis. Each kinesin has a motor domain, which converts the energy ATP hydrolysis into mechanical work and which defines a protein as a kinesin.Kinesin plays an essential role in vesicle and organelle transport. It transfers vesicles to the presynaptic axonal regions in order for the mediation of synaptic transmission to occur.The importance of kinesin is underscored by the serious medical consequences, such as diseases like Parkinson’s, Alzheimer’s and Huntington’s, which appear to implicate kinesin’s interactions with disease-associated proteins.


1.Takahiro Hamada, in International Review of Cell and Molecular Biology, 2014